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Anti-Inflammatory Drinks

Anti-Inflammatory Blueberry Smoothie

Frozen blueberries, Greek yogurt, spinach, flax and a thumb of ginger. Five minutes, 230 calories, and every ingredient is there for a reason.

By RestoreShots Editorial TeamUpdated Sep 15, 2026 6 min read
Photo: @saracervera on Unsplash

Quick answer: To make an anti-inflammatory blueberry smoothie, blend 1 cup frozen blueberries, 1/2 cup plain Greek yogurt, 1 cup unsweetened almond milk, a handful of spinach, 1 tbsp ground flaxseed, 1 tsp grated fresh ginger and 1/2 tsp cinnamon for 45 seconds. It has about 230 calories, 16g protein and 7g fiber, with no added sugar.

Key takeaways

  • Frozen blueberries work as well as fresh and make the smoothie thick without ice.
  • Ground flax, not whole seeds: whole flaxseed passes through undigested.
  • Greek yogurt is what makes it a breakfast. Without protein a fruit smoothie leaves you hungry within the hour.
  • No smoothie treats inflammation. It is one daily habit that adds fruit, fiber and omega-3 to your diet.

The recipe

Frozen blueberries in a glass blender jug on a kitchen counter
Photo: @qistiine on Unsplash

One large glass. Takes five minutes including washing the blender.

  • 1 cup (150g) frozen blueberries
  • 1/2 cup (115g) plain Greek yogurt
  • 1 cup (240ml) unsweetened almond milk, or any milk you drink
  • 1 packed cup (30g) baby spinach
  • 1 tbsp ground flaxseed
  • 1 tsp freshly grated ginger
  • 1/2 tsp ground cinnamon

Nutrition per glass

About 230 kcal, 16g protein, 31g carbohydrate (18g natural sugar from the fruit and yogurt), 7g fat and 7g fiber. Figures are estimates from USDA data; your yogurt and milk brand will move them a little. Check your own version in the smoothie calorie calculator.

How to make it

A man pouring a freshly blended smoothie from the blender jug into a glass
Photo: @willhaddock on Unsplash

Pour the milk in first so the blades catch, then add the spinach, yogurt, flax, ginger and cinnamon, and the frozen blueberries last. Blend on high for 45 seconds, until no green flecks of spinach are left.

Too thick? Add milk a splash at a time. Too thin? A few more frozen blueberries or two ice cubes. Drink it straight away; flax keeps thickening as it sits and after 20 minutes it turns closer to pudding.

Why these ingredients

Close-up of fresh blueberries covered in water droplets
Photo: @dina_nas on Unsplash

Chronic, low-grade inflammation is influenced by your whole diet, sleep, activity and weight, so be wary of any single food sold as a fix. What these ingredients do have is a reasonable body of research behind them, which is more than most "detox" blends can say.

Blueberries

Their deep colour comes from anthocyanins, among the most studied plant compounds. Small human trials with daily blueberries have reported improvements in blood vessel function and some inflammatory markers, though results vary between studies. A cup also brings 3.6g of fiber for 84 calories.

Ground flaxseed

One tablespoon supplies about 1.6g of ALA, the plant omega-3, plus 2g of fiber. Buy it ground or grind it yourself, because whole seeds pass through undigested.

Fresh ginger

Several small trials found that a couple of grams of ginger a day reduced muscle soreness after exercise. It also gives the smoothie a warm finish that stops it tasting like plain yogurt.

Spinach and Greek yogurt

Spinach adds magnesium, folate and vitamin K for 7 calories and disappears in the colour. The yogurt brings about 11g of protein, which is what keeps you full until lunch.

Frozen or fresh blueberries?

Blueberries splashing into a glass of water against a dark background
Photo: @danielacrucez on Unsplash

Frozen, for this recipe. Blueberries are frozen within hours of picking, studies comparing them with fresh berries find similar nutrient levels, and they are usually cheaper out of season. They also chill and thicken the smoothie, so you skip the ice that would water it down.

Wild blueberries, the small frozen ones, have a stronger colour and flavour than cultivated berries. Either works.

Swaps

  • Dairy-free or vegan: use unsweetened soy yogurt and soy milk; protein stays around 14g.
  • More protein: add a scoop of vanilla protein powder for about 22g more, or see our protein smoothies without powder.
  • After training: add half a banana and a scoop of protein for the carbohydrate your muscles want.
  • Golden version: add 1/2 tsp turmeric with a pinch of black pepper; the pepper is what makes the curcumin absorbable.
  • Lower sugar: swap half the blueberries for frozen cauliflower rice. You will not taste it.

More anti-inflammatory smoothies

If you want variety through the week, our 12 anti-inflammatory smoothies cover turmeric, tart cherry and ginger versions, and the 30-day protein shake builder with the Recovery goal picks berry and cherry combinations for you.

Recipes from this guide

Anti-Inflammatory6g protein

Tropical Anti-Inflammatory Smoothie

Pineapple, mango, turmeric and ginger with a little coconut for absorption. Bright, golden and quietly powerful.

Calories
280 kcal
Prep time
5 min
  • Bromelain from pineapple and curcumin from turmeric
  • Coconut fat improves curcumin absorption
Read recipe
Weight Loss22g protein

Blueberry Almond Smoothie

Frozen blueberries, almond butter and a pinch of cinnamon. It tastes like the muffin, without the sugar crash an hour later.

Calories
310 kcal
Prep time
5 min
  • Anthocyanins from a full cup of blueberries
  • 22g protein and 11g healthy fat from almond butter keep you full
Read recipe
Anti-Inflammatory24g protein

Cherry Vanilla Recovery Smoothie

Tart cherries are one of the few foods tested in athletes for muscle soreness. With Greek yogurt and flax, this is a recovery shake that tastes like dessert.

Calories
290 kcal
Prep time
5 min
  • Tart cherry anthocyanins, tested in athletes for muscle soreness
  • 24g protein for muscle repair
Read recipe

Frequently asked questions

Blueberries contain anthocyanins, and small studies with daily blueberries have reported improvements in some inflammatory markers. A blueberry smoothie with no added sugar, some protein and omega-3 seeds fits an anti-inflammatory eating pattern, but no single drink treats inflammation.

Medical disclaimer. This article is for informational purposes only and is not a substitute for professional medical advice. Consult your doctor before making changes to your diet, especially if you are pregnant, take medication or have a medical condition.

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